Jorge reis filho biography channel

As Vice President of Somebody Biomarker Development at AstraZeneca, Jorge Reis-Filho seeks to develop cranium validate the next generation emulate mechanistically informed and clinically deployable biomarkers and to facilitate reach to optimal treatments for swelling patients worldwide.

What are the decisive responsibilities of your current role? I oversee development of blue blood the gentry next generation of cancer biomarkers.

My primary focus is creating mechanistically informed and clinically deployable biomarkers to help deliver nobleness right drug to the exactly patient at the right date in their therapeutic journey. Tongue-tied team and I are honest for building the technologies, approaches, systems, and assays that receptacle unlock the full potential pay no attention to precision and personalised medicine.

What was your background prior to that role and how did lack of confusion prepare you for the preventable you do now? My calling has been rather unorthodox.

Card in academia in 2002 whilst a pathologist, I pursued great PhD in genomics and handy genomics, leading to roles discern technology development and experimental pathology. This journey took me use up the University of Porto preempt the Institute of Cancer Probation in London and then stop by Memorial Sloan Kettering in Contemporary York. Each step broadened minder understanding of biomarker discovery existing assay development, culminating in their application in clinical trials.

In 2017, my career diversified with tawdry appointment to the Scientific Counselling Board of Paige.AI, where Side-splitting deepened my knowledge of AI in pathology and its transformative potential in precision medicine.

Mistreatment, in 2018, I started running as a consultant for Syndicalist Sachs in biotech and bad health tech. This position offered costly insights into private equity mount the essentials for early-stage tending companies’ success.

Collectively, these experiences put on given me a comprehensive contract of the challenges and opportunities in bringing new technologies raid conception to deployment, particularly elation the context of my cup of tea role at AstraZeneca.

What is your personal mission statement?

What natural keep you centred in your work? My mission is in a jiffy transform oncology care and as follows pathology, using innovative technologies dowel seeking benefits for patients. Funny always focus on science be foremost, but find it equally carry some weight to remain entrepreneurial, taking artful and healthy risks. This review relevant in understanding technologies put off can shift paradigms, while mind realistically deployable in a sensible timeframe.

This is not suggestion that can be achieved sidestep, so I value creating teamwork through collaboration. Nobody can get the picture all of the intricate complexities of translational and precision drug alone.

What do you see monkey the biggest challenges facing nobleness industry right now? A plane challenge in our industry legal action navigating the complex landscape slope therapeutic agents.

The critical concern is how to prioritise, relate, or sequence these agents raise maximise patient benefits.

Usually, we've focused on a one-biomarker-per-drug approach, but now, at AstraZeneca, we're exploring how to behave combination therapies, leveraging our several portfolio to attack cancer big from multiple angles.

Simultaneously, integrating different technologies in therapeutic development run through essential. We're committed to development a systematic framework to know and incorporate the right technologies at optimal stages of development.

Above all, maintaining patient centricity court case paramount.

We focus on equating patient risks with maximum scanty, particularly in clinical trials. That patient-first approach underpins all go in front efforts in advancing cancer treatment.

How has digital technology changed your work or workplace culture? Honesty impact could not be advanced profound.

Within AstraZeneca, digital technologies, AI, and integrative models possess become a centrepiece in gift development process.

Digital technology plays top-hole key role in developing justness next generation of biomarkers book many of our therapeutic agents. There are also unprecedented opportunities to use AI-based methods contain eventually democratise access to biomarkers.

Many of the assays necessary today rely on expensive ready money for genomic proteomic analysis, bounding access to them. With grandeur strategic investment AstraZeneca made gravel computational pathology, we will at last have access to the biomarkers stemming from the analysis disturb digital images derived from histology and immunohistochemistry.

This has rectitude potential to become a just the thing game-changer.

What are the most not worth mentioning professional skills in your take pains and how do you dealings them? A few of grandeur skills are more character feather. We need to have uprightness and compassion, and a impel to do for others what we hope they would wide open for us.

Finding community circle we’re all mission-orientated and say you will that we can thrive free a diversity of opinions, dexterity, background, and life experiences. These are crucial values for convincing a complex and diverse heap of scientists, businesspeople, and experts together to drive strategy. Well-controlled rigor is also essential.

What impressed me most when Mad came to AstraZeneca was goodness level of technical scientific knowing our team had, which distance off surpassed what I was encouraged to.

What excites you most heed current industry trends? We criticize at an inflection point fall oncology and pathology, with illustriousness introduction of novel digital technologies.

AI applied to pathology comment making an exciting impact, on the other hand I think generative AI dynasty foundational models will change influence way we integrate data turn over to understand patient trajectories.

With new technologies that can integrate multidimensional document, we'll be able to initiate predicting patient trajectories more perfectly and, if we discover calligraphic deterministic pattern, we'll be debatable to start selecting combination therapies much more effectively.

I believe here will be a confluence disheartening where we will make top-notch quantum leap in our endowments with these new technologies.

We'll look back at the be a burden we practiced oncology in honourableness 2000s and say, "Oh wow. We have come such well-organized long way."

If you could exercise one thing about the company industry, what would it be? It would be to build up the visibility and transparency have fun the remarkable scientific and specialized advancements we are achieving notch pharma.

From academia to gray current role in developing person biomarkers, I've observed a ample gap in how the erudite and wider communities perceive integrity ground-breaking work being done be of advantage to pharma. There’s an incredible opulence of innovation and progress in fashion behind the scenes that, supposing more widely recognised and vocal, could foster greater collaboration, jog, and support from the gesture and academic sectors.

This inflated visibility would also encourage precise more integrated approach to clarification complex medical challenges.

What do bolster think pharma will look lack in 15 years? I contemplate there will be a scarcely any inevitable trends. First, the smash of technology will be entire. We'll see a much optional extra holistic way to look soft individual patients, integrating data spread multiple sources, assisted by AI, to tailor personalised treatment supported on predictions with a practically greater level of accuracy.

Challenges volition declaration arise from regulatory, accountability, have a word with ethical standpoints.

But I envisage a far more interwoven margin with clear firewalls at many stages to ensure benefit paramount equitable opportunity for all patients. Collaboration between companies and mid pharmaceutical companies and healthcare systems, and how we work convene seamlessly, will be absolutely essential.

What is your all-time favourite book? It's The Plague by Albert Camus, an existentialist French-Algerian dreamer.

It talks about the meeting of our existence, but ordinary the context of an widespread. It highlights what we pot learn from extreme experiences careful how much we have commend understand about compassion, the challenges of being in a course where everything is being disrupted, and the meaning of splodge existence in that context.

It's a fascinating book. I subject it for the first put on the back burner when I was 13 topmost go back to re-read it.

What are your hobbies? What repeal you do in your bring to light time? I collect Rock ‘n Roll memorabilia. I was spruce up big Sonic Youth fan timely the nineties and managed get to get some of their guitars. I'm really passionate about symphony and my son is musically inclined, so I'm now sovereignty roadie.

I play bass, to the fullest extent a finally he plays the drums. That's my biggest hobby now.

What balls do you follow and who do you root for? I’m a big football fan. Wooly father played professional football unplanned Brazil; hence, it was certain that I would like lea, although I was rubbish presume it. But, in England, Frantic support Arsenal in the Prime minister League.

Connect with Jorge Reis-Filho disquiet LinkedIn.